When River first appeared in the Library, I didn't care for her: I thought she was over-shadowing Donna (whom I adored). But when she reappeared, I fell in love with her. I guess I didn't mind her over-shadowing Amy. Now, I love the Library episodes more.
When Matt Smith was name as the 11th Doctor for the Brit sci-fi show Doctor Who, I sketched him and Amy...with the intention of making a nice drawing. I'm glad it never came to be, as I think the Doctor's chemistry with River is incredible.
River is awesome because she's more than the Doctor's equal...she's the most kick-assing-est of his sidekicks.
Long-time Whovians know the Doctor has at least one child and one grand-daughter, Susan Foreman, who was his first companion in the 1963 series. I don't know if it was ever revealed who his wife/mother of his children was, but I would love love love it if it turned out to be River.
I'm sure it could happen.
As for the drawing, I am not happy with the background, maybe I'll redo it someday.